Repository of Research and Investigative Information

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Ilam University of Medical Sciences

Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis

Sun May 26 22:39:47 2024

(2020) Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis. Eye. p. 14. ISSN 0950-222X

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Abstract

The aim of our study was to estimate regional and global cataract prevalence, its prevalence in different age groups, and the determinants of heterogeneity and its prevalence. For that, we used international databases such as PubMed, Web of Science, Scopus, Embase, and other sources of information to conduct a systematic search for all articles concerning the prevalence of age-related cataract and its types in different age groups. Of the 9922 identified articles, 45 studies with a sample size of 161,947 were included in the analysis, and most of them were from the Office for the Western Pacific Region (19 studies). Age- standardized pooled prevalence estimate (ASPPE) and 95 confidence interval (95 CI) of any cataract, cortical cataract, nuclear cataract, and posterior subcapsular (PSC) cataract were 17.20 (13.39-21.01), 8.05 (4.79-11.31), 8.22 (4.93-11.52), and 2.24 (1.41-3.07), respectively. Significant effects on heterogeneity were observed for the WHO region in the prevalence of any cataract (b: 6.30; p: 0.005) and study year in the prevalence of nuclear cataract (b: -0.66, p: 0.042). In general, the prevalence of cataract not only varies by region but also by age group, and most cases are over the age of 60 years. We examined the sources of variance in the prevalence of cataract and its different types, and identified age as a responsible factor in the prevalence of any cataract, cortical cataract, nuclear cataract, and PSC of cataract, WHO region in the prevalence of any cataract, and study year in the prevalence of nuclear cataract.

Item Type: Article
Creators:
CreatorsEmail
Hashemi, H.UNSPECIFIED
Pakzad, R.UNSPECIFIED
Yekta, A.UNSPECIFIED
Aghamirsalim, M.UNSPECIFIED
Pakbin, M.UNSPECIFIED
Ramin, S.UNSPECIFIED
Khabazkhoob, M.UNSPECIFIED
Keywords: chinese adult-population lens opacities risk-factors eye disease ultraviolet-radiation visual impairment refractive errors rural-population southern india united-states Ophthalmology
Divisions:
Page Range: p. 14
Journal or Publication Title: Eye
Journal Index: ISI
Identification Number: https://doi.org/10.1038/s41433-020-0806-3
ISSN: 0950-222X
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2628

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