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Ilam University of Medical Sciences

Prevalence of Chlamydia trachomatis in Pregnant Iranian Women: A Systematic Review and Meta-Analysis

Tue Apr 16 08:52:12 2024

(2018) Prevalence of Chlamydia trachomatis in Pregnant Iranian Women: A Systematic Review and Meta-Analysis. International Journal of Fertility & Sterility. pp. 191-199. ISSN 2008-076X

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Several studies have been conducted regarding the prevalence of Chlamydia trachomatis, Mycoplasma hominis, and Ureaplasma urealyticum in pregnant Iranian women. However, it is necessary to combine the previous results to present a general assessment. We conducted the present study based on systematic review and meta-analysis studies according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched the national and international online databases of MagIran, IranMedex, SID, MedLib, IranDoc, Scopus, PubMed, ISI Web of Knowledge, and Google Scholar search engine for certain MeSH keywords until June 16, 2017. In addition, heterogeneity, sensitivity analysis, subgroup analysis, and publication bias were performed. The data were analyzed using random-effects model and Comprehensive Meta-Analysis version 2 and P value was considered lower than 0.05. The prevalence of Chlamydia trachomatis in 11 surveyed articles that assessed 2864 pregnant Iranian women was 8.74 95% confidence interval (CI): 5.40-13.84. The prevalence of Chlamydia trachomatis was estimated 5.73% (95% CI: 2.09-14.73) and 13.55% (95% CI: 11.23-16.25) by enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR), respectively which the difference was not significant (P= 0.082). The lowest and highest prevalence of Chlamydia trachomatis was estimated in Tehran province 4.96% (95% CI: 2.45-9.810) and Ardabil province 28.60% (95% CI: 20.61-38.20), respectively. This difference was statistically significant (P< 0.001). Meta-regression for the prevalence of Chlamydia trachomatis based on year of the studies was significant with increasing slope (P= 0.017). According to the systematic review, the prevalence of Mycoplasma hominis and Urea plasma urealyticum indicated 2 to 22.8% (from 4 articles) and 9.1 to 19.8% (from 3 articles), respectively. There was no evidence of publication bias (P value for Begg and Eggers' tests was 0.161 and 0.173, respectively). The prevalence of Chlamydia trachomatis is high among pregnant Iranian women. Screening pregnant women as part of preventive measures seem necessary considering the potential for maternal and fetal complications.

Item Type: Article
Abbasalizadeh, S.UNSPECIFIED
Keywords: Chlamydia trachomatis Meta-Analysis Mycoplasma Hominis Pregnant Women Ureaplasma Urealyticum sexually-transmitted infections pelvic-inflammatory-disease mycoplasma-genitalium preterm birth risk epidemiology centers Obstetrics & Gynecology
Page Range: pp. 191-199
Journal or Publication Title: International Journal of Fertility & Sterility
Journal Index: ISI
Volume: 12
Number: 3
Identification Number:
ISSN: 2008-076X
Depositing User: مهندس مهدی شریفی

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