Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The effect of celery (Apium graveolens L.) on fertility: A systematic review

Sun Oct 2 16:13:48 2022

(2018) The effect of celery (Apium graveolens L.) on fertility: A systematic review. Journal of Complementary and Integrative Medicine. ISSN 15533840 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction. Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were "Apium graveolens L.", "fertility", "reproductive system", "sperm", "testis", "delivery", "sexual hormone", "LH", "FSH", "testosterone", "semen", "male", and "female". Out of 238 collected articles (published in the period 1995 to 2015), 222 were excluded due to non-relevance and lack of access to the original article. The notable points were the different results seen by different researchers during different treatment periods or at different doses. Of the 16 studies reviewed in this study, 13 studies have mentioned the positive effect of celery on fertility, while three studies reported the inhibitory effects of this plant. Celery can have protective effects against substances such as sodium valproate, propylene glycol, and diethyl phthalate causing damages to the testicular structure and spermatogenesis. In this regard, the doses used and the treatment time while using the plant must be accurately investigated. Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration. © 2018 Walter de Gruyter GmbH, Berlin/Boston.

Item Type: Article
Creators:
CreatorsEmail
Kooti, W.UNSPECIFIED
Moradi, M.UNSPECIFIED
Peyro, K.UNSPECIFIED
Sharghi, M.UNSPECIFIED
Alamiri, F.UNSPECIFIED
Azami, M.UNSPECIFIED
Firoozbakht, M.UNSPECIFIED
Ghafourian, M.UNSPECIFIED
Keywords: Apium graveolens L. fertility reproductive celery extract follitropin luteinizing hormone phthalic acid diethyl ester plant extract propylene glycol sex hormone testosterone unclassified drug valproic acid protective agent Article celery childbirth drug effect genital system human nonhuman obstetric delivery reproduction sperm spermatogenesis systematic review testis injury chemically induced female infertility male testis Apium graveolens Humans Plant Extracts Protective Agents
Divisions:
Journal or Publication Title: Journal of Complementary and Integrative Medicine
Journal Index: Scopus
Volume: 15
Number: 2
Identification Number: https://doi.org/10.1515/jcim-2016-0141
ISSN: 15533840 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2538

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