Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Experimental study on Wistar rats: the Allium eriophyllum Boiss aqueous extract ointment effectively treat induced cutaneous wound

Wed Feb 28 22:41:54 2024

(2019) Experimental study on Wistar rats: the Allium eriophyllum Boiss aqueous extract ointment effectively treat induced cutaneous wound. Comparative Clinical Pathology. ISSN 16185641 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Cutaneous wound healing by medicinal plants which have fewer side effects than chemical drugs have been on the increase. In our study, we evaluated cutaneous wound healing potential of Allium eriophyllum Boiss aqueous extract ointment in rats. In in vivo design, after creating the cutaneous wound on the back of the rats, the animals were randomly divided into four groups: untreated control, treatment with Eucerin ointment, treatment with 3 tetracycline ointment, treatment with 3 A. eriophyllum aqueous extract ointment. The groups were treated for 30 days. For biochemical and histopathological analysis of the cutaneous wound healing trend, a 3 × 3 cm section was prepared from all dermal thicknesses on days 10, 20, and 30. The data were analyzed by SPSS 21 software. The use of A. eriophyllum aqueous extract ointment in the treatment groups led to remarkable reduce (p < 0.05) in the levels of wound area, total cells, neutrophil, lymphocyte, and macrophage, and remarkable increase (p < 0.05) in the levels of wound contracture, hydroxyl proline, hexosamine, hexuronic acid, fibrocyte, and the rate of fibrocyte to fibroblast as compared to the control and basal ointment groups. According to the findings, A. eriophyllum aqueous extract ointment can cure the cutaneous wound. © 2019, Springer-Verlag London Ltd., part of Springer Nature.

Item Type: Article
Creators:
CreatorsEmail
Goorani, S.UNSPECIFIED
Morovvati, H.UNSPECIFIED
Zangeneh, M. M.UNSPECIFIED
Zangeneh, A.UNSPECIFIED
Seydi, N.UNSPECIFIED
Moradi, R.UNSPECIFIED
Keywords: Allium eriophyllum Boiss Aqueous extract Cutaneous wound healing Ointment
Divisions:
Journal or Publication Title: Comparative Clinical Pathology
Journal Index: Scopus
Identification Number: https://doi.org/10.1007/s00580-019-02986-z
ISSN: 16185641 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2510

Actions (login required)

View Item View Item