Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Shared Pathological Mechanisms Between Diabetes Mellitus and Neurodegenerative Diseases

Wed Dec 7 06:51:37 2022

(2019) Shared Pathological Mechanisms Between Diabetes Mellitus and Neurodegenerative Diseases. Current Pharmacology Reports. pp. 219-231. ISSN 2198641X (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Neurodegeneration is a term for the description of the progressive neuronal and neural structure loss, function, and their populations in the central nervous system (CNS). Recent studies have shed light on shared pathological mechanisms including inflammation, mitochondrial dysfunction, and oxidative stress between diabetes mellitus (DM) and neurodegenerative disorders. The association between these age-related chronic diseases has attracted immense attention during the past decade. Because shared mechanisms may underlie the co-occurrence of DM and neurodegeneration, deep understanding about the potential links between these conditions may be helpful for a better management of both diseases. In the present review, we attempt to provide an overview on the relationship pathways between DM and chronic neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and amyotrophic lateral sclerosis (ALS). © 2019, Springer Nature Switzerland AG.

Item Type: Article
Creators:
CreatorsEmail
Nasrolahi, A.UNSPECIFIED
Mahmoudi, J.UNSPECIFIED
Noori-Zadeh, A.UNSPECIFIED
Haghani, K.UNSPECIFIED
Bakhtiyari, S.UNSPECIFIED
Darabi, S.UNSPECIFIED
Keywords: Alzheimer’s disease Amyotrophic lateral sclerosis Diabetes mellitus Huntington’s disease Neurodegenerative diseases Parkinson’s disease
Divisions:
Page Range: pp. 219-231
Journal or Publication Title: Current Pharmacology Reports
Journal Index: Scopus
Volume: 5
Number: 4
Identification Number: https://doi.org/10.1007/s40495-019-00191-8
ISSN: 2198641X (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2485

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