Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients

Thu Dec 8 06:11:54 2022

(2019) The pulsed ultrasound strategy effectively decreases the S. aureus population of chronic rhinosinusitis patients. BMC research notes. p. 576. ISSN 1756-0500 (Electronic) 1756-0500 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/31519221

Abstract

OBJECTIVE: Staphylococcus aureus with the ability of biofilm formation and the drug resistance acquisition is one of the most frequently isolated pathogens from chronic rhinosinusitis patients. Ultrasound as an alternative therapy is effectively able to kill the bacteria by cavitation in or on the bacterial cells and peroxide generation and hence improving antibiotic treatment efficacy. RESULTS: Staphylococcus aureus was detected in 4 and 6 out of 14 patients by phenotypic and qPCR assays, respectively. Four patients were completely resolved after pulsed ultrasound treatment. However, presence of the S. aureus was confirmed in three healthy controls by bacterial cultivation. Pulsed ultrasound have been quantitatively decreased the S. aureus population in chronic rhinosinusitis patients (p < 0.05). Further studies need to be investigated the effectiveness of pulsed ultrasound as an alternative course of CRS patient's treatment.

Item Type: Article
Creators:
CreatorsEmail
Feizabadi, N.UNSPECIFIED
Sarrafzadeh, J.UNSPECIFIED
Fathali, M.UNSPECIFIED
Vasaghi-Gharamaleki, B.UNSPECIFIED
Dadgoo, M.UNSPECIFIED
Kardan-Yamchi, J.UNSPECIFIED
Kazemian, H.UNSPECIFIED
Hesam-Shariati, S.UNSPECIFIED
Feizabadi, M. M.UNSPECIFIED
Keywords: Chronic rhinosinusitis Pulsed ultrasound Real-time PCR Staphylococcus aureus Treatment
Divisions:
Page Range: p. 576
Journal or Publication Title: BMC research notes
Journal Index: Pubmed
Volume: 12
Number: 1
Identification Number: https://doi.org/10.1186/s13104-019-4579-3
ISSN: 1756-0500 (Electronic) 1756-0500 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2452

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