Repository of Research and Investigative Information

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Ilam University of Medical Sciences

The association between anemia and postpartum depression: A systematic review and meta-analysis

Thu Aug 11 15:56:36 2022

(2019) The association between anemia and postpartum depression: A systematic review and meta-analysis. Caspian Journal of Internal Medicine. pp. 115-124. ISSN 2008-6164

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Abstract

Background: The association between anemia and postpartum depression (PPD) has been reported to be controversial in different studies. Therefore, this study aimed to provide a comprehensive assessment of anemia and PPD. Methods: This review study was conducted according to the MOOSE protocol and results have been reported according to the PRISMA guideline. We searched epidemiologic studies published until January 2018 in nine English databases including Scopus, PubMed/Medline, Science Direct, Embase, Web of Science, CINAHL, Cochrane Library, EBSCO and Google Scholar using English MeSH keywords. The heterogeneity of the studies was assessed using the Cochran's Q test and I-2 index. Data were analyzed using a random effects model and comprehensive meta-analysis (CMA) software version 2. Results: In the 10 studies, the association between postpartum anemia and PPD was significant (heterogeneity test: P< 0.001, I-2=74.62), and RR=1.887 (95 CI: 1.255-2.838, P=0.002). In 8 studies, anemia during pregnancy significantly increased the risk of postpartum depression (heterogeneity test: P=0.116, I-2=36.422), RR=1.240 (1.001-1.536, P=0.048). The subgroup analysis of postpartum anemia and PPD was not significant for the variables of quality of studies, study design, and the period of evaluating depression and anemia. The subgroup analysis of anemia during pregnancy and PPD was not significant for the period of evaluating depression. Publication bias did not affect the results of the studies. Conclusion: Meta-analysis results showed anemia during pregnancy and after pregnancy that significantly increased the risk of postpartum depression. Therefore, prevention, identification and treatment of anemia in pregnant women seem necessary.

Item Type: Article
Creators:
CreatorsEmail
Azami, M.UNSPECIFIED
Badfar, G.UNSPECIFIED
Khalighi, Z.UNSPECIFIED
Qasemi, P.UNSPECIFIED
Shohani, M.UNSPECIFIED
Soleymani, A.UNSPECIFIED
Abbasalizadeh, S.UNSPECIFIED
Keywords: Anemia Postpartum Depression Meta-Analysis low-birth-weight maternal anemia low hemoglobin preterm birth mental-health pregnancy risk quality women prevalence General & Internal Medicine
Divisions:
Page Range: pp. 115-124
Journal or Publication Title: Caspian Journal of Internal Medicine
Journal Index: ISI
Volume: 10
Number: 2
Identification Number: https://doi.org/10.22088/cjim.10.2.115
ISSN: 2008-6164
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2430

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