Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Association between the risk factors for cardiovascular disorders and coronary artery occlusion on angiography

Tue Jun 25 13:12:32 2024

(2018) Association between the risk factors for cardiovascular disorders and coronary artery occlusion on angiography. Iranian Heart Journal. pp. 38-45. ISSN 17357306 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: coronary artery occlusion is the main reason for cardiovascular disease-related deaths the world over. Hence, identifying its main determinants is essential for the proper prevention of coronary artery disease and its-related mortality and morbidity. The present study investigated the association between cardiovascular risk factors and the occlusion of coronary arteries in patients. Methods: In this cross-sectional study, the medical records of 2046 consecutive patients with suspected cardiovascular disorders who were referred to the Angiography Center at Imam Hossein Hospital in the Iranian province of Ilam between January 2010 and January 2012 were reviewed via census sampling. Based on the angiography findings, the patients were classified as normal or involved coronary artery groups. The risk factors for cardiovascular disorders were also recorded. Binary and multivariable logistic regression models were used to determine the adjusted odds ratio (OR) for each risk factor. Results: In the final multivariable regression modeling, the variables of gender (OR=3.44 and 95 CI: 1.02 to 5.58), age (OR=1.10 and 95 CI: 1.05 to 1.15), a family history of coronary disease (OR=1.12 and 95 CI: 1.30 to 1.94), current smoking (OR=1.50 and 95 CI: 1.02 to 1.98), systolic blood pressure (OR=1.16 and 95 CI: 1.05 to 1.28), diastolic blood pressure (OR=1.04 and 95 CI: 1.00 to 1.09), and high-density lipoprotein cholesterol (HDL-C) (OR=1.04 and 95 CI: 1.00 to 1.08) significantly increased the risk for coronary artery occlusion. Conclusions: Among the different non-modifiable variables, gender, age, and a family history of CAD and among the modifiable variables, smoking, hypertension, and a reduced HDL-C level increased the risk for coronary involvement. Further cohort studies and meta-analyses are required to clarify the causative association between these risk factors and coronary occlusion. © 2018, Iranian Heart Association. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Bidel, Z.UNSPECIFIED
Hemmati, R.UNSPECIFIED
Nazarzadeh, M.UNSPECIFIED
Delpisheh, A.UNSPECIFIED
Keywords: Angiography Cardiovascular disease Risk factor
Divisions:
Page Range: pp. 38-45
Journal or Publication Title: Iranian Heart Journal
Journal Index: Scopus
Volume: 19
Number: 3
ISSN: 17357306 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2342

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