Repository of Research and Investigative Information

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Ilam University of Medical Sciences

Candiduria in Hospitalized Patients and Identification of Isolated Candida Species by Morphological and Molecular Methods in Ilam, Iran

Sat Oct 1 17:41:52 2022

(2019) Candiduria in Hospitalized Patients and Identification of Isolated Candida Species by Morphological and Molecular Methods in Ilam, Iran. Iranian Journal of Public Health. pp. 156-161. ISSN 2251-6085

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Abstract

Background: Candiduria in hospitalized patients may represent contamination, colonization, or urinary tract infections. On the other hand, candidemia and upper urinary tract infection could be the complications of candiduria. The aim of this study was to determine candiduria in hospitalized patients and identify isolated Candida species by conventional and molecular methods. Methods: This cross-sectional study was conducted on hospitalized patients in Imam Khomeini and Mostafa Khomeini hospitals in Ilam, western Iran from Jan to Dec 2016. Urine samples of hospitalized patients were collected during a period of 4 months for diagnosis of candiduria. Primary identification was done by conventional methods. PCR profile was carried out using phenol-chloroform method and confirmed using restriction fragment length polymorphism (PCR-RFLP) technique by MspI restriction enzyme. Results: Candiduria was diagnosed in 18 (9.2) cases from a total of 195 patients. Isolated yeasts were identified as C. albicans (n: 13), C. glabrata (n: 5), and C. parapsilosis (n: 1) in the one case both C. albicans and C. glabrata were isolated from a urine sample. Conclusion: Candida urinary tract infection is becoming increasingly common in hospitalized patients but, differentiation fungal colonization from infection and identification of etiologic agents for optimal treatment is necessary.

Item Type: Article
Creators:
CreatorsEmail
Fazeli, A.UNSPECIFIED
Kordbacheh, P.UNSPECIFIED
Nazari, A.UNSPECIFIED
Daie Ghazvini, R.UNSPECIFIED
Mirhendi, H.UNSPECIFIED
Safara, M.UNSPECIFIED
Bakhshi, H.UNSPECIFIED
Yaghoubi, R.UNSPECIFIED
Keywords: Hospitalized patients Candiduria Candida albicans Candida spp. Yeast renal-transplant recipients urinary-tract-infections Public, Environmental & Occupational Health
Divisions:
Page Range: pp. 156-161
Journal or Publication Title: Iranian Journal of Public Health
Journal Index: ISI
Volume: 48
Number: 1
ISSN: 2251-6085
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/2276

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