Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Proteomic analysis in human fibroblasts by continuous exposure to extremely low-frequency electromagnetic fields

Thu Aug 11 16:32:54 2022

(2007) Proteomic analysis in human fibroblasts by continuous exposure to extremely low-frequency electromagnetic fields. Pakistan Journal of Biological Sciences. pp. 4108-4112. ISSN 10288880 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Most people are Exposed to Extremely Low-Frequency Electromagnetic Fields (ELF-EMF). A number of studies have indicated association between exposure to extremely low frequency electromagnetic fields and a variety of cancers. Recently some therapeutic techniques such as repetitive Transcranial Magnetic Stimulation (rTMS) have been used to study localization of brain function, connectively of brain regions and pathophysiology of neuropsychiatric disorders (rTMS utilize low frequency-electromagnetic field). Here, the effect of continuous ELF electromagnetic fields (3 Hz, sinusoidal, 3 h and 4 mT) on the protein expression of human fibroblast cells is investigated via proteomics. The comparison of the 2-DE separated proteins from the exposed and sham (control) cells showed that some protein expressions are affected by radiation. The two proteins that their expression are reduced about 50 are determined as alpha 1 antitrypsin (A1AT) and Transthyretin (TTR). As it is reported that the amounts of these proteins reduced in the pathological conditions it can be concluded that application of ELF-EMF in therapeutic aspects may be to accompanying with their side effects. © 2007 Asian Network for Scientific Information.

Item Type: Article
Creators:
CreatorsEmail
Seyyedi, S. S.UNSPECIFIED
Dadras, M. S.UNSPECIFIED
Tavirani, M. R.UNSPECIFIED
Mozdarani, H.UNSPECIFIED
Toossi, P.UNSPECIFIED
Zali, A. R.UNSPECIFIED
Keywords: Alpha 1 antitrypsin and transthyretin ELF-EMF Human fibroblast cells
Divisions:
Page Range: pp. 4108-4112
Journal or Publication Title: Pakistan Journal of Biological Sciences
Journal Index: Scopus
Volume: 10
Number: 22
Identification Number: https://doi.org/10.3923/pjbs.2007.4108.4112
ISSN: 10288880 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1670

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