Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The effect of dexamethasone on morbidity related to vomiting, pain and oral intake in children after tonsillectomy

Fri Dec 2 16:45:50 2022

(2009) The effect of dexamethasone on morbidity related to vomiting, pain and oral intake in children after tonsillectomy. Journal of Clinical and Diagnostic Research. pp. 1641-1646. ISSN 0973709X (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background and Aim: Morbidity related to postoperative nausea and vomiting, pain, poor oral intake, dehydration and fever is a concern in children undergoing tonsillectomy. The aim of this study was to investigate the effects of preoperative 0.5 mg/kg i.v. dexamethasone on postoperative quality oral intake, vomiting and pain in paediatric patients undergoing tonsillectomy with or without adenoidectomy, during the first 8 hours of the postoperative period. Material and Methods: This is a quasi-experimental study that was performed at the Ilam Imam Khomeini hospital, IR, during the year 2008-2009. In a randomized, double-blind trial, 66 paediatric patients undergoing tonsillectomy received IV placebo (saline) or 0.5mg/kg IV dexamethasone, after the induction of anaesthesia before surgery. The incidence of vomiting, the time to the first oral intake, the quality of oral intake and the pain score were compared in both groups during the first 8 hours of the postoperative period. Pain was assessed using a five-point "faces" scale (1 = smiling face: no pain, 5 = crying face: highest pain score). The quality of the oral intake was judged as follows: excellent = child requests it, good = child accepts it when offered, fair = child accepts it when coaxed, and poor = child refuses. All collected data were analyzed using the statistical software (SPSS, Ver.11.5), descriptive statistics, Student t test, Mann-Whitney test and the ×2 or Fisher's exact tests. p < 0.05 was considered significant. Results: The overall incidence of vomiting was significantly less in the Dexamethasone group as compared to the Saline group (p<0.001). The time of the first oral intake was shorter in the Dexamethasone group as compared to the Saline group (P<0.05). The quality of oral intake was better in the Dexamethasone group than in the Saline group (P<0.001). When compared with placebo, the patients who received preoperative dexamethasone had a significantly less pain score during the first 8 hours postoperatively (p < 0.05). Discussion and conclusion: In the paediatric patients undergoing tonsillectomy, preoperative dexamethasone use significantly reduced posttonsillectomy pain, improved oral intake and decreased vomiting without any significant side effects. This report confirms the beneficial effect of IV dexamethasone on postoperative morbidity related to vomiting, pain and oral intake in children after tonsillectomy and is recommended for routine use.

Item Type: Article
Creators:
CreatorsEmail
Khani, A.UNSPECIFIED
Jaafarpour, M.UNSPECIFIED
Khajavikhan, J.UNSPECIFIED
Dyrekvandmogadam, A.UNSPECIFIED
Keywords: Children Dexamethasone Pain Tonsillectomy Vomiting sodium chloride adenoidectomy article child child care clinical trial controlled clinical trial controlled study double blind procedure drug effect feeding behavior female food intake human incidence major clinical study male morbidity pain assessment postoperative pain postoperative period postoperative vomiting preoperative treatment randomized controlled trial unspecified side effect
Divisions:
Page Range: pp. 1641-1646
Journal or Publication Title: Journal of Clinical and Diagnostic Research
Journal Index: Scopus
Volume: 3
Number: 4
ISSN: 0973709X (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1656

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