Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Antinociceptive and anti-inflammatory effects of hydroalchoholic extract of Anethum graveolens L. seed

(2010) Antinociceptive and anti-inflammatory effects of hydroalchoholic extract of Anethum graveolens L. seed. Journal of Medicinal Plants. pp. 124-130. ISSN 16840240 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: There are many reports about anti-inflammatory effect of Anethum graveolens L.(A.g) in Iranian traditional medicine. In current decade, based on using of neutriceuticales for healing, the use of herbal drugs became very common. Objective: In this study, regarding the mentioned purposes, we have evaluated anti-inflammatory and antinociceptive effects of Hydroalchoholic Extract of A.g seeds. Methods: In this research, male mice were used and in inflammatory test they were divided to 6 groups: control, dexamethasone (15 mg/kg), seed A.g. extract (100,200, 400,500mg/kg). All of the drugs were administered intraperitonally. The inflammation was caused by xylene-induced ear oedema. In order to evaluate the antinocicetive of Anethum graveolens L. seed, we used formalin test. Mice were divided to 6 groups: control, seed A.g. extract (100,200, 400, 500 mg/kg). AU of drugs were administered intraperitonally. Results: The results indicated that A.g. extract has anti-inflammatory and antinociceptive effects. Conclusion: This study suggests A.g extract as a candidate for pain relieving for further studies.

Item Type: Article
Keywords: Anthum graveolens L. seed Formalin test Inflammation Nociception Xylene-induced ear oedema analgesic agent Anethum graveolens extract antiinflammatory agent dexamethasone unclassified drug xylene animal experiment antiinflammatory activity antinociception article dill drug effect edema male mouse nonhuman plant seed Anethum graveolens Mus
Divisions:
Page Range: pp. 124-130
Journal or Publication Title: Journal of Medicinal Plants
Journal Index: Scopus
Volume: 9
Number: 34
ISSN: 16840240 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1650

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