Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Contribution of diet and major depression to incidence of acute myocardial infarction (AMI)

(2010) Contribution of diet and major depression to incidence of acute myocardial infarction (AMI). Lipids in Health and Disease. ISSN 1476511X (ISSN)

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Abstract

Background. Despite significant improvements in the treatment of coronary heart disease (CHD), it is still a major cause of mortality and morbidity among the Iranian population. Epidemiological studies have documented that risk factors including smoking and the biochemical profile are responsible for the development of acute myocardial infarction (AMI). Psychological factors have been discussed as potential risk factors for coronary heart disease. Among emotional factors, depression correlates with coronary heart disease, particularly myocardial infarction. Methods. This case-control study was conducted on 120 cases (69 males and 51 females) of acute myocardial infarction (AMI) and 120 controls, with a mean age of 62.48 ± 15.39 years. Cases and controls were matched by age, residence and sex. Results. The results revealed that severe depression was independently associated with the risk of AMI (P = 0.025, OR = 2.6, 95 CI 1.1-5.8). The analysis of variables indicated that risk factors for developing depression were unmarried, low levels of polyunsaturated fatty acids (PUFAs), total dietary fiber (TDF) and carbohydrates. The levels of these dietary factors were lowest in severely depressed patients compared to those categorised as moderate or mild cases. Furthermore, severely depressed subjects were associated with higher levels of total cholesterol, high systolic blood pressure (SBP) and WHR. Age, income, a family history of coronary heart disease, education level, sex, employment and smoking were not associated with severe depression. Conclusion. The present study demonstrated that severe depression symptoms are independent risk factors for AMI. Furthermore, severe depression was associated with an unhealthy diet and AMI risk factors. © 2010 Yary et al; licensee BioMed Central Ltd.

Item Type: Article
Keywords: carbohydrate glucose high density lipoprotein low density lipoprotein polyunsaturated fatty acid triacylglycerol unsaturated fatty acid acute heart infarction adult analysis of variance article blood pressure measurement blood sampling cardiovascular risk case control study cholesterol blood level clinical assessment controlled study diet diet restriction dietary fiber dietary intake electrocardiogram female food frequency questionnaire glucose blood level human incidence major clinical study major depression male risk assessment systolic blood pressure triacylglycerol blood level aged carbohydrate diet heart infarction middle aged pathophysiology risk factor Case-Control Studies Depressive Disorder, Major Dietary Carbohydrates Fatty Acids, Unsaturated Humans Myocardial Infarction Risk Factors
Journal or Publication Title: Lipids in Health and Disease
Journal Index: Scopus
Volume: 9
Identification Number: https://doi.org/10.1186/1476-511X-9-133
ISSN: 1476511X (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1646

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