Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Castleman's disease in a patient with inguinal mass mimicking hernia

Tue Jul 23 21:21:27 2024

(2010) Castleman's disease in a patient with inguinal mass mimicking hernia. American Journal of Case Reports. pp. 211-213. ISSN 19415923 (ISSN)

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Background: Hernias comprise approximately 7 of all surgical outpatient visits, and occur more commonly in the groin. Inguinal hernia is a protrusion of abdominal cavity contents through the inguinal canal. It is very common in surgery, and lifetime risk is reported to be 27 for men and 3 for women. Castleman's is a rare disease, characterized clinically by hypertrophy of lymph nodes and histologically by angiofollicular lymph node hyperplasia. It may occur throughout the lifespan from adolescence to the seventh decade. Case Report: A 27-year-old workman was referred to the emergency department for left inguinal pain with increasing severity when standing and walking. Except for nausea and vomiting, he had no other symptoms. Upon palpation, a left inguinal, hard and tender mass was found. Laboratory data and chest X-ray were normal. A total surgical excision was performed under general anesthesia. Histological assessment revealed an extensive capillary proliferation and a lymphocyte predominant infltrate surrounded by small germinal centers, confrming Castleman's disease. Conclusions: Considering the importance of differential diagnosis of inguinal hernia, Castleman's disease can mimic the signs and symptoms of inguinal hernia, and it should be considered in suspected cases of inguinal mass. © The American Journal of Case Reports, 2010.

Item Type: Article
Hafezi-Ahmadi, M.UNSPECIFIED
Keywords: Castleman's disease Inguinal hernia Lymphadenopathy adult anamnesis angiofollicular lymph node hyperplasia article capillary proliferation case report differential diagnosis emergency ward excision germinal center histopathology human laboratory test lymphocytic infiltration male physical examination symptomatology thorax radiography
Page Range: pp. 211-213
Journal or Publication Title: American Journal of Case Reports
Journal Index: Scopus
Volume: 11
ISSN: 19415923 (ISSN)
Depositing User: مهندس مهدی شریفی

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