Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran

Sat Jun 25 09:13:35 2022

(2011) The prevalence of ESBLs producing Klebsiella pneumoniae isolates in some major hospitals, Iran. Open Microbiology Journal. pp. 91-95. ISSN 18742858 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Aims of this study were to investigate on antibiotic resistance and molecular epidemiology of K.pneumoniae producing ESBLs isolates of respiratory tract infections in some major hospitals in Iran. K.pneumonaie were obtained of patients with RTI. K. pneumoniae producing ESBLs detected by screening, confirming and PCR methods. During the 12-month period, a total of one hundred and thirteen of K.pneumoniae were found from RTI in three cities in different region of Iran which Sixty seven strains (59.2) were ESBLs producer. In Ilam hospitals, seventeen strains (43.6), in Milad hospital, thirty-seven strains (74) and in Emam Reza hospital, thirteen strains (54.2) were ESBLs producer. The findings showed that among sixty-seven K.pneumoniae producing ESBLs, Sixty-three strains (94) were positive for blaSHV, eleven strains (16.4) contained blaTEM and sixteen strains (23.9) harbored blaCTX-M. Imipenem was found as an effectiveness antibiotic. In the current study, Majority of the ESBLs production had occurred in Milad hospital in Tehran (74). In conclusion, spreading ESBL-producing strains is a concern, as it causes limitations to the antimicrobial agents for optimal treatment of patients. © Ghafourian et al.

Item Type: Article
Creators:
CreatorsEmail
Ghafourian, S.UNSPECIFIED
Sekawi, Z. B.UNSPECIFIED
Sadeghifard, N.UNSPECIFIED
Mohebi, R.UNSPECIFIED
Neela, V. K.UNSPECIFIED
Maleki, A.UNSPECIFIED
Hematian, A.UNSPECIFIED
Rhabar, M.UNSPECIFIED
Raftari, M.UNSPECIFIED
Ranjbar, R.UNSPECIFIED
Keywords: Blactx-m Blashv Blatem Esbls Klebsiella pneumoniae amikacin antiinfective agent aztreonam cefotaxime cefpodoxime ceftazidime ceftriaxone ciprofloxacin clavulanic acid cotrimoxazole extended spectrum beta lactamase imipenem antibiotic resistance article bacterial strain bacterium isolate city controlled study hospital Iran molecular epidemiology nonhuman polymerase chain reaction prevalence priority journal respiratory tract infection screening
Divisions:
Page Range: pp. 91-95
Journal or Publication Title: Open Microbiology Journal
Journal Index: Scopus
Volume: 5
Identification Number: https://doi.org/10.2174/1874285801105010091
ISSN: 18742858 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1623

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