Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Prediction of myocardial infarction using Weibull accelerated failure time model: A population based study

Sun Aug 14 02:16:30 2022

(2013) Prediction of myocardial infarction using Weibull accelerated failure time model: A population based study. Iranian Journal of Endocrinology and Metabolism. pp. 538-548. ISSN 16834844 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Introduction: Cardiovascular diseases rank first among causes of death in Iran and most other countries. Determination of the risk factors of these diseases and their importance in the incidence of myocardial infarction is very important in formulating preventive programs for these diseases. This study was designed to evaluate the relationship between the risk factors of heart diseases and the time to event for myocardial Infarction using the Weibull model. Materials and Methods: In the TGLS study, 5183 men and women, aged over 30 years, without cardiovascular disease from the East of Tehran were studied. Data were analyzed using Weibull distribution and Cox proportional hazard models. Results: During 6.5 years of follow up, a total of 83 new cases of MI (53 men and 30 women) accured. Cumulative incidence of MI was 0.0025. The Weibull multivariate regression model, showed significant relationships between FBS, sex, SBP and smoking and MI Wiebull regression models, showed that FBS levels over 126 mg/dl, adjusted for age, sex, LDL, SBP, DBP, HDL and TG, decrease time to MI by 2.87 compared to normal persons. Conclusion: Variables of FBS, age, sex, LDL, SBP, DBP, HDL, TG, and smoking are the most important predictive factors of Myocardial Infarction.

Item Type: Article
Creators:
CreatorsEmail
Sayehmiri, K.UNSPECIFIED
Alizadeh, S.UNSPECIFIED
Motedayen, M.UNSPECIFIED
Azizi, F.UNSPECIFIED
Keywords: Myocardial infarction Prediction time Risk factors Weibull distribution glucose low density lipoprotein triacylglycerol adult article clinical evaluation diastolic blood pressure female glucose blood level heart disease heart infarction human incidence major clinical study male proportional hazards model risk factor smoking systolic blood pressure weibull accelerated failure time model
Divisions:
Page Range: pp. 538-548
Journal or Publication Title: Iranian Journal of Endocrinology and Metabolism
Journal Index: Scopus
Volume: 14
Number: 6
ISSN: 16834844 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1583

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