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Ilam University of Medical Sciences

Comparative effect of cinnamon and ibuprofen for treatment of primary dysmenorrhea: A randomized double-blind clinical trial

Wed Nov 30 07:11:36 2022

(2015) Comparative effect of cinnamon and ibuprofen for treatment of primary dysmenorrhea: A randomized double-blind clinical trial. Journal of Clinical and Diagnostic Research. QC04-QC07. ISSN 2249782X (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background and Aims: Primary dysmenorrheal has a negative impact on women's quality of life. The purpose of this study was to compare the effect of Cinnamon and Ibuprofen for treatment of primary dysmenorrheal in a sample of Iranian female college students from Ilam University of Medical Sciences (western Iran). Materials and Methods: In a randomized, double-blind trial, out of 114, control group received placebo (empty capsules contain starch, TDS, n= 38) a test group received Ibuprofen (capsule containing 400mg Ibuprofen, TDS, n=38), or another test group received Cinnamon (capsule containing 420 mg Cinnamon, TDS, n= 38) in 24 h. To determine severity of pain, we used the VAS scale. Pain intensity and duration of pain were monitored in the group during first 72 h of cycle.Results: The mean pain severity score and mean duration of pain in Ibuprofen and Cinnamon were less than placebo group respectively (p< 0.001). Of 4 hours after the intervention there were no statistically significant differences between the Cinnamon and placebo group (p> 0.05). Of eight hours after the intervention, the mean pain severity in the cinnamon group was significantly lower than placebo group (p< 0.001). At various time intervals the mean pain severity in the Ibuprofen group were significantly less than Cinnamon and placebo groups (p< 0.001). Conclusion: Cinnamon compared with placebo significantly reduced the severity and duration of pain during menstruation, but this effect was lower compared with Ibuprofen. Cinnamon can be regarded as a safe and effective treatment for primary dysmenorrhea. More researches are recommended to study the efficacy of Cinnamon on reducing menstrual bleeding. © 2015, Journal of Clinical and Diagnostic Research. All Rights Reserved.

Item Type: Article
Creators:
CreatorsEmail
Jaafarpour, M.UNSPECIFIED
Hatefi, M.UNSPECIFIED
Khani, A.UNSPECIFIED
Khajavikhan, J.UNSPECIFIED
Keywords: Medicinal herbal Menstruation Pain ibuprofen placebo adult Article bleeding cinnamon controlled study double blind procedure dysmenorrhea experimental study female human Iranian people major clinical study pain intensity pain severity randomized controlled trial visual analog scale Cinnamomum verum
Divisions:
Page Range: QC04-QC07
Journal or Publication Title: Journal of Clinical and Diagnostic Research
Journal Index: Scopus
Volume: 9
Number: 4
Identification Number: https://doi.org/10.7860/JCDR/2015/12084.5783
ISSN: 2249782X (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1454

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