Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Effects of vitamin B6 on premenstrual syndrome: A systematic review and meta-Analysis

Tue Feb 27 20:03:10 2024

(2016) Effects of vitamin B6 on premenstrual syndrome: A systematic review and meta-Analysis. Journal of Chemical and Pharmaceutical Sciences. pp. 1346-1353. ISSN 09742115 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background and Objective: Premenstrual syndrome (PMS) refers to a range of physical and psychological symptoms which regularly occur during the luteal phase of a menstrual cycle and disappear short after menstruation starts. Considering the negative effects of PMS on women's daily life, various treatments have been developed to alleviate its symptoms. Vitamin B6 is one of the complementary therapies used to treat PMS. The present meta-Analysis aimed to investigate the effects of vitamin B6 on PMS. Methodology: Different databases including PubMed, ISI, Scopus, SID, Magiran, Science Direct, and Medlib were searched to identify studies addressing the effects of vitamin B6 on PMS. The relevant data obtained from these papers were analyzed by a random-effects model. Data were analyzed using R Ver. 3.2.3 Software and STATA. Results: There were significant reductions in the mean scores of PMS after treatment with vitamin B6 compare to control groups. Moreover, the mean PMS scores of the two groups were also significantly different after the treatment. The mean difference between the two groups was -1.19 95% CI: -1.94,-0.44; P = 0.002. Significant reductions were also observed in physical symptoms (P = 0.006) and psychological symptoms (P < 0.001) of PMS after the intervention. Conclusion: The results of our meta-Analysis confirmed vitamin B6 as a beneficial, inexpensive, and effective treatment for PMS symptoms. Therefore, the administration of this treatment option will enable midwives to achieve the important goal of reducing PMS symptoms.

Item Type: Article
Creators:
CreatorsEmail
Soheila, S.UNSPECIFIED
Faezeh, K.UNSPECIFIED
Kourosh, S.UNSPECIFIED
Fatemeh, S.UNSPECIFIED
Nasrollah, N.UNSPECIFIED
Mahin, G.UNSPECIFIED
Asadi-Samani, M.UNSPECIFIED
Bahmani, M.UNSPECIFIED
Keywords: Female Physical symptoms Premenstrual syndrome Psychological symptoms Vitamin B6 placebo pyridoxine Article clinical effectiveness clinical evaluation comparative study data base drug effect human managed care Medline mental disease meta analysis (topic) physical disease ScienceDirect Scopus symptom assessment systematic review
Divisions:
Page Range: pp. 1346-1353
Journal or Publication Title: Journal of Chemical and Pharmaceutical Sciences
Journal Index: Scopus
Volume: 9
Number: 3
ISSN: 09742115 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1410

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