Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Effects of immunization to hepatitis B vaccine in Iranian health staff: A systematic review and meta-analysis study

Thu Dec 8 12:42:45 2022

(2016) Effects of immunization to hepatitis B vaccine in Iranian health staff: A systematic review and meta-analysis study. Koomesh. pp. 789-795. ISSN 16087046 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Introduction: Hepatitis B causes liver inflammation in human and is one of the major health problems worldwide. Currently, about 2 billion people are estimated to be infected with Hepatitis B worldwide. Various studies have reported different immune responses to hepatitis B vaccine (HBV) in Iranian health staff, while there is not any estimate of overall responses. Therefore, the present study was conducted to determine the immune response to HBV among health staff in Iran using meta-analysis method. Materials and Methods: This study was a systematic review of Iran databases related to the subject of immune response to HBV, including; Magiran, Iran medex, Iran Doc, SID, Med lib and international databases including Scopus, Pub med, Science Direct, and also Google Scholar search engine. Only those articles that have had inclusion criteria were included. To combine the results of different random effects of studies, the meta-analysis was used. Results: There were 1084 subjects included in 9 studies. The immune response to HBV in health staff was 86.7 (CI: 95, 80.9-92.6) after 1.21 years of last vaccination. This rate was estimated to be 93.5 for males (CI: 95, 89.3-97.6) and 90.7 for females (CI: 95, 84.9-96.5). The minimum and maximum vaccine responsewere reported from Tehran (70.6) and Yazd (99.2), respectively. Conclusion: The immunization to HBV in healthcare personnel was more than 80 after 1.21 years of last vaccination. Therefore, performing the complete course of hepatitis B vaccination for prevention of infection would be sufficient and booster dose would not be required. © 2016, Semnan University of Medical Sciences. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Azami, M.UNSPECIFIED
Nikpey, S.UNSPECIFIED
Pakzad, I.UNSPECIFIED
Sayehmiri, K.UNSPECIFIED
Keywords: Health personnel Hepatitis B Immunization Meta-Analysis hepatitis B vaccine female health care personnel human immune response Iranian people major clinical study male medical staff meta analysis public health problem Review systematic review vaccination
Divisions:
Page Range: pp. 789-795
Journal or Publication Title: Koomesh
Journal Index: Scopus
Volume: 17
Number: 4
ISSN: 16087046 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1356

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