Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Prevalence of diabetes mellitus in Iranian patients with thalassemia major: A systematic review and meta-analysis

Fri Apr 19 02:32:31 2024

(2016) Prevalence of diabetes mellitus in Iranian patients with thalassemia major: A systematic review and meta-analysis. Journal of Mazandaran University of Medical Sciences. pp. 192-204. ISSN 17359279 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background and purpose: Diabetes mellitus is one of the most common endocrine complications in thalassemic patients. Several studies investigated the prevalence of diabetes in Iranian patients with thalassemia major and reported different results but no overall estimate was calculated. Therefore, we conducted a meta-analysis to study the prevalence of diabetes in patients with thalassemia major in Iran. Materials and methods: This review study was conducted by PRISMA checklist. Electronic databases including Magiran, Iranmedex, SID, Medlib, IranDoc, Scopus, Pubmed, Science direct, Cochrane, Web of Science, Springer, Online Library Wiley and Google Scholar were searched in chronological order without time limit, in January 2016, using relevant keywords. Two researchers independently performed article selection and data extraction. All studies meeting our inclusion criteria were investigated. Data analysis was done using random effect model in Stata Ver.11.1. Conclusion: Overall, 6380 patients were studied in 42 articles. Prevalence of diabetes in patients with thalassemia major in Iran was 9.5 (CI: 95, 7.8-11.3). The minimum and maximum prevalence of diabetes were found in West (10.3) and North of Iran (8.3), respectively. The prevalence rate in male and female thalassemia major patients were 12.6 (CI: 95, 6.1-19.1) and 10.8 (CI: 95, 8.2-14.5), respectively. Results: Prevalence of diabetes in Iranian patients with thalassemia major was found to be high. Therefore, routine blood tests should be done every six-month for early diagnosis of diabetes in this population. © 2016, Mazandaran University of Medical Sciences. All rights reserved.

Item Type: Article
Creators:
CreatorsEmail
Azami, M.UNSPECIFIED
Sayehmiri, K.UNSPECIFIED
Keywords: Diabetes mellitus Meta-analysis Thalassemia major bibliographic database gender human Iran meta analysis prevalence Review systematic review
Divisions:
Page Range: pp. 192-204
Journal or Publication Title: Journal of Mazandaran University of Medical Sciences
Journal Index: Scopus
Volume: 26
Number: 141
ISSN: 17359279 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1347

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