Abstract

Background: Acinetobacter baumannii is one of the most important opportunistic pathogens responsible for several nosocomial infections. A major problem in treatment is antibiotic resistance. Methods: By searching international and national databases, including PubMed, Google Scholar, Web of Science, SID, Magiran, IranDoc and IranMedex, 38 articles between years 2002 to 2016 published world-wide were extracted and analyzed using the meta-analysis method and random effects model. The heterogeneity of studies was assessed using the I2 index. Data were analyzed with the R and STATA (Ver 11/2) software. Results: Forty-three articles were selected for this study. Drug-resistance of Acinetobacter baumannii towards Polymyxin was reported as 5, yet for Colistin 4 was estimated. Resistance rates to Polymyxin and Colistin in the continent of America and Asia was 6 and Sensitivity rate to Polymyxin and Colistin was 96 and 80, respectively. Conclusions: Given that drug resistance rate of Acinetobacter baumannii to Polymyxin and Colistin in this study was 5 and 4, respectively, thus indicating high sensitivity of Acinetobacter baumannii to these antibiotics, this group can be administered as appropriate therapeutic agents against these bacteria. © 2017, Shiraz E-Medical Journal.