Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Association of mitochondrial dysfunction and lipid metabolism with type 2 diabetes mellitus: A review of literature

Thu Oct 6 07:53:40 2022

(2018) Association of mitochondrial dysfunction and lipid metabolism with type 2 diabetes mellitus: A review of literature. Frontiers in Biology. pp. 406-417. ISSN 16747984 (ISSN)

Full text not available from this repository.

Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: Diabetes mellitus (DM) is one of the most prevalent chronic diseases, and its prevalence continues to increase globally. The impact of mitochondrial dysfunction and lipid metabolism on diabetes mellitus and insulin resistance (IR) has been implicated in several previous reports; however, the results of studies are confusing despite four decades of study. Methods/Results: This review has evaluated updated understanding of the role of mitochondrial dysfunction and lipid metabolism on type 2 diabetes, and found that mitochondrial dysfunction and lipid metabolism disorder induce the dysregulation of liver and pancreatic beta cells, insulin resistance, and type 2 diabetes. Conclusion: Mitochondrial dysfunction and lipid metabolism induce metabolic dysregulation and finally increasing the possibility of diabetes. © 2018, Higher Education Press and Springer-Verlag GmbH Germany, part of Springer Nature.

Item Type: Article
Creators:
CreatorsEmail
Haghani, K.UNSPECIFIED
Asadi, P.UNSPECIFIED
Taheripak, G.UNSPECIFIED
Noori-Zadeh, A.UNSPECIFIED
Darabi, S.UNSPECIFIED
Bakhtiyari, S.UNSPECIFIED
Keywords: Insulin resistance Lipid metabolism Mitochondrial dysfunction Type 2 diabetes
Divisions:
Page Range: pp. 406-417
Journal or Publication Title: Frontiers in Biology
Journal Index: Scopus
Volume: 13
Number: 6
Identification Number: https://doi.org/10.1007/s11515-018-1521-3
ISSN: 16747984 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1204

Actions (login required)

View Item View Item