Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Lethal Pneumocystis jiroveci pneumonia 24 Years After Kidney Transplantation

Mon Aug 8 18:14:03 2022

(2014) Lethal Pneumocystis jiroveci pneumonia 24 Years After Kidney Transplantation. Nephro-urology monthly. e13605. ISSN 2251-7006 (Print) 2251-7006 (Linking)

Full text not available from this repository.

Official URL: https://www.ncbi.nlm.nih.gov/pubmed/24783169

Abstract

INTRODUCTION: Pneumocystis jiroveci is an opportunistic infectious fungus in immunosuppressed patients, particularly in ones with acquired immunodeficiency syndrome (AIDS). The use of immunosuppressive drugs especially corticosteroids predisposes the transplanted patients to a variety of infectious diseases including Pneumocystis infection. In many developed countries, the incidence of Pneumocystis jiroveci pneumonia (PJP) is dwindling in transplant patients receiving appropriate prophylaxis. In this study, definitive diagnosis of Pneumocystis infection in a patient receiving kidney transplant was presented. CASE PRESENTATION: The patient was a 45-year-old man with a history of kidney transplantation 24 years ago, admitted to a specialized hospital in Tehran because of fever and respiratory distress. Upon admission, the patient showed symptoms of unconsciousness and shortness of breath. Paraclinical tests and complementary examinations such as microscopic observation and molecular analysis confirmed the definitive diagnosis of Pneumocystis infection. Specific treatment with trimethoprim/sulfamethoxazole was carried out alongside other therapeutic measures; but unfortunately the patient did not respond to the specific treatment and died in the course of a progressive disease. DISCUSSION: The disease progress in these patients can still be fast and deadly. Applying rapid molecular diagnostic techniques to start appropriate and timely treatment is essential. Utilization of such diagnostic methods is recommended in our country.

Item Type: Article
Creators:
CreatorsEmail
Rezavand, B.UNSPECIFIED
Hosseini, M. J.UNSPECIFIED
Izadi, M.UNSPECIFIED
Mahmoodzadeh Poornaki, A.UNSPECIFIED
Sadraei, J.UNSPECIFIED
Einollahi, B.UNSPECIFIED
Rezaimanesh, M. R.UNSPECIFIED
Bagheri, O.UNSPECIFIED
Abdi, J.UNSPECIFIED
Keywords: Kidney Transplantation Pneumonia, Pneumocystis jiroveci Polymerase Chain Reaction
Divisions:
Page Range: e13605
Journal or Publication Title: Nephro-urology monthly
Journal Index: Pubmed
Volume: 6
Number: 2
Identification Number: https://doi.org/10.5812/numonthly.13605
ISSN: 2251-7006 (Print) 2251-7006 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1146

Actions (login required)

View Item View Item