Repository of Research and Investigative Information

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Ilam University of Medical Sciences

Melatonin improve the sperm quality in forced swimming test induced oxidative stress in nandrolone treated Wistar rats

Mon Aug 8 18:09:42 2022

(2014) Melatonin improve the sperm quality in forced swimming test induced oxidative stress in nandrolone treated Wistar rats. Acta medica Iranica. pp. 496-504. ISSN 1735-9694 (Electronic) 0044-6025 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/25135257

Abstract

This study investigates the effects of melatonin on the sperm quality and testis weight after the combination of swimming exercise and nandrolone decanoate (DECA). Two groups of male Wistar rats were treated for eight weeks as follows; group A consist of CO (control), Sham, N (DECA), S (swimming) and NS (DECA plus swimming); and group B: Sham M (sham melatonin), M (melatonin), MN (melatonin plus DECA), MS (melatonin plus swimming), MNS (melatonin, DECA plus swimming). The motility of sperm was significantly improved in melatonin groups in comparison to N, S and NS groups (P</=0.05). The left testes weight was decreased in N, NS and MNS groups, and the right testes weight was decreased in N,S,NS, MS and MNS groups in compare with the control group. This study concluded that melatonin probably could improve the sperm motility and sex organs weight after the combination of DECA and exercise.

Item Type: Article
Creators:
CreatorsEmail
Minaii, B.UNSPECIFIED
Moayeri, A.UNSPECIFIED
Shokri, S.UNSPECIFIED
Habibi Roudkenar, M.UNSPECIFIED
Golmohammadi, T.UNSPECIFIED
Malek, F.UNSPECIFIED
Barbarestani, M.UNSPECIFIED
Keywords: Anabolic Agents/pharmacology Animals Antioxidants/pharmacology Disease Models, Animal Humans Male Melatonin/*pharmacology Nandrolone/*analogs & derivatives/pharmacology Nandrolone Decanoate Oxidative Stress/*drug effects Physical Conditioning, Animal Rats Rats, Wistar Semen Analysis Spermatozoa/drug effects/*metabolism *Swimming
Divisions:
Page Range: pp. 496-504
Journal or Publication Title: Acta medica Iranica
Journal Index: Pubmed
Volume: 52
Number: 7
ISSN: 1735-9694 (Electronic) 0044-6025 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1137

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