Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Anti-fungal resistance in candida isolated from oral and diaper rash candidiasis in neonates

Mon Aug 8 18:12:29 2022

(2014) Anti-fungal resistance in candida isolated from oral and diaper rash candidiasis in neonates. Bioinformation. pp. 667-70. ISSN 0973-2063 (Print) 0973-2063 (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/25512681

Abstract

The purpose of the present study is to evaluate the sensitivity of Candida species isolated from oral candidiasis and diaper dermatitis infections in children. The children referring to private and public clinics in Ilam, Iran were exmined for oral candidiasis and diaper dermatitis. In this study, 248 oral candidiasis and diaper dermatitis samples were collected and cultured.Candida species were identified by using standard methods. Resistance and sensitivity to amphotericin B, nystatin, ketoconazole, fluconazole, itraconazole, clotrimazole, and posaconazole were determined using the CLSI M44-A standard disk diffusion method. From the 248 studied samples, 149 were positive for Candida, among which the Candida albicans was the most prevalent (64.4). The resistance of different Candida species to nystatin, itraconazole, fluconazole, ketoconazole, clotrimazole, voriconazole, and posaconazole were 4, 43, 34.2, 34.9, 21.5, 6, and 6.7, respectively. No resistance to amphotericin B was observed. Considering rather low resistance to nystatin, this drug is the best choice for oral candidiasis and diaper dermatitis.

Item Type: Article
Creators:
CreatorsEmail
Mohamadi, J.UNSPECIFIED
Motaghi, M.UNSPECIFIED
Panahi, J.UNSPECIFIED
Havasian, M. R.UNSPECIFIED
Delpisheh, A.UNSPECIFIED
Azizian, M.UNSPECIFIED
Pakzad, I.UNSPECIFIED
Keywords: Diaper dermatitis Drug resistance Oral candidiasis
Divisions:
Page Range: pp. 667-70
Journal or Publication Title: Bioinformation
Journal Index: Pubmed
Volume: 10
Number: 11
Identification Number: https://doi.org/10.6026/97320630010667
ISSN: 0973-2063 (Print) 0973-2063 (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1120

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