Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Oral Colonization by Nosocomial Pathogens During Hospitalization in Intensive Care Unit and Prevention Strategies

Wed Nov 30 07:33:53 2022

(2017) Oral Colonization by Nosocomial Pathogens During Hospitalization in Intensive Care Unit and Prevention Strategies. Recent patents on anti-infective drug discovery. pp. 8-20. ISSN 2212-4071 (Electronic) 1574-891X (Linking)

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/28215171

Abstract

BACKGROUND: Critically ill patients are very susceptible to a variety of disorders and infections during hospitalization in Intensive Care Units ICU. Among these problems, nosocomial infections are major causes of morbidity and mortality. METHODS: Nosocomial pneumonias, specifically ventilator associated pneumonias have become a major health care issue. The implication of oral care in hospital presents challenges that can prevent or reduce the risk of nosocomial pneumonias in ICU. In this review article, we reviewed the most important nosocomial pathogens which colonize the oral cavity and causes severe infections during hospitalization in ICU. CONCLUSION: Finally, we discuss that the prevention strategies against oral colonization of nosocomial pathogens include classical methods and novel methods such as Photodynamic therapy, NO based therapy, anti-virulence therapy and other new under investigation antimicrobial strategies.

Item Type: Article
Creators:
CreatorsEmail
Kazemian, H.UNSPECIFIED
Bourbour, S.UNSPECIFIED
Beheshti, M.UNSPECIFIED
Bahador, A.UNSPECIFIED
Keywords: Anti-Bacterial Agents/therapeutic use Bacteria/isolation & purification/*pathogenicity *Biofilms Hospitalization/statistics & numerical data Hospitals/statistics & numerical data Humans Incidence Intensive Care Units/*statistics & numerical data Mouth/*microbiology/physiopathology Opportunistic Infections/epidemiology/*microbiology/prevention & control Oral Hygiene/methods Photochemotherapy Pneumonia, Ventilator-Associated/epidemiology/*microbiology/prevention & control Probiotics/therapeutic use Quorum Sensing/drug effects Critically ill patients Icu Staphylococcus aureus nosocomial infection oral colonization probiotics.
Divisions:
Page Range: pp. 8-20
Journal or Publication Title: Recent patents on anti-infective drug discovery
Journal Index: Pubmed
Volume: 12
Number: 1
Identification Number: https://doi.org/10.2174/1574891X12666170215152854
ISSN: 2212-4071 (Electronic) 1574-891X (Linking)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1046

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