Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

Association between T3, T4, and TSH hormones proportion and Toxoplasma gondii anti-IgG seroprevalence in patients suffering from clinical and drug-controlled thyroid dysfunctions in southeastern Iran

Wed May 18 17:41:08 2022

(2021) Association between T3, T4, and TSH hormones proportion and Toxoplasma gondii anti-IgG seroprevalence in patients suffering from clinical and drug-controlled thyroid dysfunctions in southeastern Iran. Turk Hijyen ve Deneysel Biyoloji Dergisi. pp. 299-306. ISSN 03779777 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Objective: Toxoplasma gondii is an important agent responsible for many hormonal and behavioral disorders in humans. The main objective of this study was to evaluate the hypothesis that ‘T. gondii infection interferes with thyroid hormones secretion or thyroid drug treatment'. Methods: This is a cross-sectional study that involved 249 patients suffering from thyroid dysfunctions, divided into 3 groups: hypothyroidism (n=107), hyperthyroidism (n=96), and drug-controlled thyroid disorders (n=91), referred to Seyedoshohada Kerman private clinic. Serum samples were tested for thyroid-stimulating hormone (TSH), triiodothyronine (T3), and thyroxine (T4) along with Toxoplasma anti-IgG using ELISA technique. Demographic information was collected using a demographic Results: The seroprevalence of Toxoplasma gondii IgG antibodies among patients with hypothyroidism, hyperthyroidism, and drug-controlled thyroid disorders was 22.4, 19.8, and 22 respectively. The mean value of thyroid hormones of positive T. gondii samples in hypothyroidism, hyperthyroidism, and drug-controlled thyroid disorders was TSH=7.95, T3=1.12, T4=2.36; TSH=0.14, T3=1.42, T4=7.85; and TSH=2.75, T3=1.12, T4=1.45 respectively. The seropositivity of Toxoplasma gondii infection was 40.4 among individuals with a history of contact with pets and 26.3 among the rural dwellers. Conclusion: There was no significant difference between T. gondii infection among the three study groups. A comparison of serum levels of thyroid hormones between infected and non-infected individuals in the above-mentioned groups illustrated that latent toxoplasmosis wasn't significantly associated with thyroid hormones secretion. Also, contact with pets and the rural lifestyle has a positive association with T. gondii seroprevalence. © 2021. All Rights Reserved.

Item Type: Article
Creators:
CreatorsEmail
Raissi, V.UNSPECIFIED
Alizadeh, G.UNSPECIFIED
Bayat, F.UNSPECIFIED
Akhlaghi, E.UNSPECIFIED
Getso, M.UNSPECIFIED
Raiesi, O.UNSPECIFIED
Abdollahi, A.UNSPECIFIED
İbrahim, A.UNSPECIFIED
Akbari, S.UNSPECIFIED
Navi, Z.UNSPECIFIED
Etemadi, S.UNSPECIFIED
Keywords: cross-sectional study hipertiroidizm hipotiroidizm hyperthyroidism hypothyroidism kesitsel çalışma T3 T4 Toxoplasma gondii TSH
Divisions:
Page Range: pp. 299-306
Journal or Publication Title: Turk Hijyen ve Deneysel Biyoloji Dergisi
Journal Index: Scopus
Volume: 78
Number: 3
Identification Number: https://doi.org/10.5505/TURKHIJYEN.2021.95825
ISSN: 03779777 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/3795

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