Repository of Research and Investigative Information

Repository of Research and Investigative Information

Ilam University of Medical Sciences

The prevalence of antibiotic resistance to polymyxins in clinical isolates of acinetobacter baumannii in Iran and the world: A systematic review and meta-analysis

Fri May 20 03:07:14 2022

(2017) The prevalence of antibiotic resistance to polymyxins in clinical isolates of acinetobacter baumannii in Iran and the world: A systematic review and meta-analysis. Shiraz E Medical Journal. ISSN 17351391 (ISSN)

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Official URL: https://www.scopus.com/inward/record.uri?eid=2-s2....

Abstract

Background: Acinetobacter baumannii is one of the most important opportunistic pathogens responsible for several nosocomial infections. A major problem in treatment is antibiotic resistance. Methods: By searching international and national databases, including PubMed, Google Scholar, Web of Science, SID, Magiran, IranDoc and IranMedex, 38 articles between years 2002 to 2016 published world-wide were extracted and analyzed using the meta-analysis method and random effects model. The heterogeneity of studies was assessed using the I2 index. Data were analyzed with the R and STATA (Ver 11/2) software. Results: Forty-three articles were selected for this study. Drug-resistance of Acinetobacter baumannii towards Polymyxin was reported as 5, yet for Colistin 4 was estimated. Resistance rates to Polymyxin and Colistin in the continent of America and Asia was 6 and Sensitivity rate to Polymyxin and Colistin was 96 and 80, respectively. Conclusions: Given that drug resistance rate of Acinetobacter baumannii to Polymyxin and Colistin in this study was 5 and 4, respectively, thus indicating high sensitivity of Acinetobacter baumannii to these antibiotics, this group can be administered as appropriate therapeutic agents against these bacteria. © 2017, Shiraz E-Medical Journal.

Item Type: Article
Creators:
CreatorsEmail
Sayehmiri, F.UNSPECIFIED
Alikhani, M. Y.UNSPECIFIED
Sayehmiri, K.UNSPECIFIED
Karami, M.UNSPECIFIED
Ghaderkhani, J.UNSPECIFIED
Keywords: Acinetobacter baumannii Antibiotics Colistin Polymyxins Prevalence of Resistance
Divisions:
Journal or Publication Title: Shiraz E Medical Journal
Journal Index: Scopus
Volume: 18
Number: 12
Identification Number: https://doi.org/10.5812/semj.57580
ISSN: 17351391 (ISSN)
Depositing User: مهندس مهدی شریفی
URI: http://eprints.medilam.ac.ir/id/eprint/1275

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